Risk factors for mortality in adult COVID-19 patients: frailty predicts fatal outcome in older patients
et al., International Journal of Infectious Diseases,
Retrospective 255 hospitalized patients, 65 treated with HCQ, showing unadjusted RR 0.87, p=0.63. Confounding by indication is likely.
risk of death, 13.4% lower, RR 0.87, p = 0.63, treatment 16 of 65 (24.6%), control 54 of 190 (28.4%), NNT 26.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
This study is excluded in the after exclusion results of meta
substantial unadjusted confounding by indication likely, unadjusted results with no group details.
Tehrani et al., 10/30/2020, retrospective, Sweden, Europe, peer-reviewed, 5 authors.