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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 13% Improvement Relative Risk c19hcq.com/tehrani.html Favors HCQ Favors control
30 October 2020 - Late treatment study
Risk factors for mortality in adult COVID-19 patients: frailty predicts fatal outcome in older patients
Tehrani et al., International Journal of Infectious Diseases, doi:10.1016/j.ijid.2020.10.071 (Peer Reviewed)
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Retrospective 255 hospitalized patients, 65 treated with HCQ, showing unadjusted RR 0.87, p=0.63. Confounding by indication is likely.
risk of death, 13.4% lower, RR 0.87, p = 0.63, treatment 16 of 65 (24.6%), control 54 of 190 (28.4%), NNT 26.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
This study is excluded in the after exclusion results of meta analysis: substantial unadjusted confounding by indication likely, unadjusted results with no group details.
Tehrani et al., 10/30/2020, retrospective, Sweden, Europe, peer-reviewed, 5 authors.
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