7/14 Late treatment study
et al., Research Square, doi:10.21203/rs.3.rs-39421/v1 (Preprint)
High in-hospital mortality due to COVID-19 in a community hospital in Spain: a prospective observational study
High in-hospital mortality due to COVID-19 in a community hospital in Spain: a prospective observational study
Retrospective 100 hospitalized patients in Spain showing lower mortality with HCQ+AZ.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Trullàs et al., 7/14/2020, retrospective, Spain, Europe, preprint, median age 75.0, 8 authors.
risk of death, 35.6% lower, RR 0.64, p = 0.12, treatment 20 of 66 (30.3%), control 16 of 34 (47.1%).
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
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