2/1 Late treatment study
et al., Critical Care Research and Practice, 10.1155/2021/7510306 (Peer Reviewed)
COVID-19: A Single-Center ICU Experience of the First Wave in the Philippines
COVID-19: A Single-Center ICU Experience of the First Wave in the Philippines
Retrospective ICU patients in the Philippines showing unadjusted HCQ RR 0.82, p = 0.64.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
Ubaldo et al., 2/1/2021, retrospective, Philippines, Asia, peer-reviewed, 3 authors.
risk of death, 18.4% lower, RR 0.82, p = 0.64, treatment 17 of 25 (68.0%), control 5 of 6 (83.3%), COVID-19 positive patients.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.
