2/1 Late treatment study
et al., Critical Care Research and Practice, 10.1155/2021/7510306 (Peer Reviewed)
COVID-19: A Single-Center ICU Experience of the First Wave in the Philippines
COVID-19: A Single-Center ICU Experience of the First Wave in the Philippines
Retrospective ICU patients in the Philippines showing unadjusted HCQ RR 0.82, p = 0.64.
Ubaldo et al., 2/1/2021, retrospective, Philippines, Asia, peer-reviewed, 3 authors.
risk of death, 18.4% lower, RR 0.82, p = 0.64, treatment 17 of 25 (68.0%), control 5 of 6 (83.3%), COVID-19 positive patients.
This study is excluded in the after exclusion results of meta analysis: substantial unadjusted confounding by indication likely, very late stage, ICU patients, unadjusted results with no group details.
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.
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