Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
et al., Virol. J. 2:69, 2005, doi:10.1186/1743-422X-2-69 (In Vitro)
In Vitro study, SARS-CoV-1, not included in the study count or percentages. CQ has strong antiviral effects on SARS CoV infection when cells treated either before or after exposure, suggesting prophylactic and treatment use. Describes three mechanisms by which the drug might work and suggests it may have both a prophylactic and therapeutic role in coronavirus infections.
Vincent et al., 1/1/2005, peer-reviewed, 8 authors.
In Vitro studies are an important part of preclinical research, however results may be very different in vivo.
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