Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus
et al., Phytomedicine, doi:10.1016/j.phymed.2020.153333 (In Vitro)
In Vitro study providing novel insights into the molecular mechanism of CQ/HCQ treatment, showing that CQ and HCQ both inhibit the entrance of 2019-nCoV into cells by blocking the binding of the virus with ACE2.
Wang et al., 9/2/2020, peer-reviewed, 34 authors.
In Vitro studies are an important part of preclinical research, however results may be very different in vivo.
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