ICU and ventilator mortality among critically ill adults with COVID-19

4/26 Late treatment study

Auld et al., Critical Care Medicine, doi:10.1097/ccm.0000000000004457 (Peer Reviewed)
ICU and ventilator mortality among critically ill adults with COVID-19

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Retrospective 217 critically ill patients, 114 receiving HCQ, showing no significant difference in mortality.

Auld et al., 4/26/2020, retrospective, USA, North America, peer-reviewed, 14 authors.

risk of death, 2.8% higher, RR 1.03, p = 1.00, treatment 33 of 114 (28.9%), control 29 of 103 (28.2%).

Effect extraction follows pre-specified rules prioritizing more serious outcomes. For an individual study the most serious outcome may have a smaller number of events and lower statistical signficance, however this provides the strongest evidence for the most serious outcomes when combining the results of many trials.

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