et al., Critical Care Medicine, doi:10.1097/ccm.0000000000004457 (Peer Reviewed)
Retrospective 217 critically ill patients, 114 receiving HCQ, showing no significant difference in mortality.
Auld et al., 4/26/2020, retrospective, USA, North America, peer-reviewed, 14 authors.
risk of death, 2.8% higher, RR 1.03, p = 1.00, treatment 33 of 114 (28.9%), control 29 of 103 (28.2%).
Effect extraction follows pre-specified rules
prioritizing more serious outcomes. For an individual study the most serious
outcome may have a smaller number of events and lower statistical signficance,
however this provides the strongest evidence for the most serious outcomes
when combining the results of many trials.