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Home   COVID-19 treatment studies for Vitamin D  COVID-19 treatment studies for Vitamin D  C19 studies: Vitamin D  Vitamin D   Select treatmentSelect treatmentTreatmentsTreatments
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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 86% Improvement Relative Risk Mortality (b) 63% Mortality (c) 23% c19vitamind.com/bennouar.html Favors vitamin D Favors control
12 January 2021 - Analysis of outcomes based on serum levels
Vitamin D Deficiency and Low Serum Calcium as Predictors of Poor Prognosis in Patients with Severe COVID-19
Bennouar et al., Journal of the American College of Nutrition, doi:10.1080/07315724.2020.1856013 (Peer Reviewed)
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Prospective study of 120 severe cases of COVID-19 in Algeria finding low vitamin D and low calcium both associated with increased mortality.
risk of death, 85.5% lower, RR 0.14, p = 0.002, high D levels 4 of 30 (13.3%), low D levels 15 of 32 (46.9%), NNT 3.0, adjusted per study, >30μg/l vs. <10μg/l, proportional Cox regression.
risk of death, 63.0% lower, RR 0.37, p = 0.10, high D levels 4 of 30 (13.3%), low D levels 14 of 35 (40.0%), NNT 3.7, adjusted per study, >30μg/l vs. 10-19μg/l, proportional Cox regression.
risk of death, 23.1% lower, RR 0.77, p = 0.73, high D levels 4 of 30 (13.3%), low D levels 4 of 23 (17.4%), NNT 25, adjusted per study, >30μg/l vs. 20-29μg/l, proportional Cox regression.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
Bennouar et al., 1/12/2021, prospective, Algeria, Africa, peer-reviewed, 4 authors.
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