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0 0.25 0.5 0.75 1 1.25 1.5 1.75 2+ Mortality 19% Improvement Relative Risk c19vitamind.com/krishnand.html Favors vitamin D Favors control
20 July 2020 - Late treatment study
Clinical comorbidities, characteristics, and outcomes of mechanically ventilated patients in the State of Michigan with SARS-CoV-2 pneumonia
Krishnan et al., J Clin Anesth., doi:10.1016/j.jclinane.2020.110005 (Peer Reviewed)
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Retrospective 152 mechanically ventilated patients in the USA showing unadjusted lower mortality with vitamin C, vitamin D, HCQ, and zinc treatment, statistically significant only for vitamin C.
risk of death, 19.0% lower, RR 0.81, p = 0.42, treatment 8 of 16 (50.0%), control 84 of 136 (61.8%), NNT 8.5.
Effect extraction follows pre-specified rules prioritizing more serious outcomes.
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
Krishnan et al., 7/20/2020, retrospective, USA, North America, peer-reviewed, 13 authors, dosage not specified.
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