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0 0.5 1 1.5 2+ Case 46% Improvement Relative Risk c19hcq.com Patel et al. HCQ for COVID-19 PrEP Favors HCQ Favors control
Patel, 11,468 patient HCQ prophylaxis study: 46% fewer cases [p=0.001] https://c19p.org/patel4
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Factors Associated with COVID-19 Breakthrough Infection in the Pre-Omicron Era Among Vaccinated Patients with Rheumatic Diseases: A Cohort Study
Patel et al., medRxiv, doi:10.1101/2022.07.13.22277606 (Preprint)
15 Jul 2022    Source   PDF   Share   Tweet
Retrospective 11,468 vaccinated rheumatic disease patients in the USA, showing lower risk of COVID-19 with HCQ/CQ use compared with all other treatments. Adjusted results are only provided with respect to specific other treatments.
risk of case, 46.3% lower, RR 0.54, p = 0.001, treatment 28 of 18,358 (0.2%), control 223 of 78,509 (0.3%), cases vs. total person-months, unadjusted.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
This study is excluded in the after exclusion results of meta analysis: unadjusted results with no group details.
Patel et al., 7/15/2022, retrospective, USA, preprint, mean age 60.0, 12 authors.
Contact: zswallace@mgh.harvard.edu, jsparks@bwh.harvard.edu.
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