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All Studies   Meta Analysis    Recent:   
0 0.5 1 1.5 2+ Mortality 58% Improvement Relative Risk Ventilation 74% ICU admission 70% HCQ for COVID-19  Tsanovska et al.  LATE TREATMENT Is late treatment with HCQ beneficial for COVID-19? PSM prospective study of 140 patients in Bulgaria (Nov - Dec 2020) Lower mortality (p=0.031) and ventilation (p=0.00066) c19hcq.org Tsanovska et al., Infectious Disorders.., Mar 2022 Favors HCQ Favors control

Hydroxychloroquine (HCQ) treatment for hospitalized patients with COVID-19

Tsanovska et al., Infectious Disorders - Drug Targets, doi:10.2174/1871526522666220303121209
Mar 2022  
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HCQ for COVID-19
1st treatment shown to reduce risk in March 2020
 
*, now known with p < 0.00000000001 from 422 studies, recognized in 42 countries.
No treatment is 100% effective. Protocols combine complementary and synergistic treatments. * >10% efficacy in meta analysis with ≥3 clinical studies.
4,100+ studies for 60+ treatments. c19hcq.org
PSM prospective study of 260 COVID-19 patients in Bulgaria, showing lower mortality, ventilation, and ICU admission with HCQ treatment.
risk of death, 57.9% lower, RR 0.42, p = 0.03, treatment 8 of 70 (11.4%), control 19 of 70 (27.1%), NNT 6.4, propensity score matching.
risk of mechanical ventilation, 73.9% lower, RR 0.26, p < 0.001, treatment 6 of 70 (8.6%), control 23 of 70 (32.9%), NNT 4.1, propensity score matching.
risk of ICU admission, 70.4% lower, RR 0.30, p < 0.001, treatment 8 of 70 (11.4%), control 27 of 70 (38.6%), NNT 3.7, propensity score matching.
Effect extraction follows pre-specified rules prioritizing more serious outcomes. Submit updates
Tsanovska et al., 3 Mar 2022, prospective, Bulgaria, peer-reviewed, 8 authors, study period 6 November, 2020 - 28 December, 2020.
This PaperHCQAll
Late treatment
is less effective
Please send us corrections, updates, or comments. c19early involves the extraction of 100,000+ datapoints from thousands of papers. Community updates help ensure high accuracy. Treatments and other interventions are complementary. All practical, effective, and safe means should be used based on risk/benefit analysis. No treatment or intervention is 100% available and effective for all current and future variants. We do not provide medical advice. Before taking any medication, consult a qualified physician who can provide personalized advice and details of risks and benefits based on your medical history and situation. FLCCC and WCH provide treatment protocols.
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